Epidermolysis Bullosa Simplex: Apremilast Study

We are investigating whether apremilast can improve symptoms in patients over 6 years old with epidermolysis bullosa simplex. The study will also look at the safety of the treatment and how it affects quality of life.

3-6 months ≤5 visits Efficacy phase (II)No Placebo Standard Medicines OralDermatologyRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Apremilast

Apremilast is a pill that helps control symptoms of psoriasis and psoriatic arthritis by reducing inflammation.

Otezla

Otezla is a medicine used to treat plaque psoriasis and psoriatic arthritis, helping reduce skin plaques and joint pain.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Apremilast

Apremilast is a substance that reduces inflammation to help treat conditions like psoriasis and psoriatic arthritis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Afimax

Aperzyx

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hopital Necker Enfants Malades

Dermatology

Montrouge, France

Centre Hospitalier Universitaire De Nice

Dermatology

Nice, France

Assistance Publique Hopitaux De Paris

Dermatology

Quinze-Vingts, France

Sponsor: Centre Hospitalier Universitaire De Nice

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.