Esketamine for Schizophrenia Symptoms

We are studying whether esketamine can reduce depressive and negative symptoms in people with schizophrenia. The trial also looks at whether it causes any worsening of psychotic symptoms.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dibondrin
Ketanest S
Ketanest S is an anesthetic medicine used to put patients to sleep and relieve pain during surgeries and medical procedures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Diphenhydramine Hydrochloride
Diphenhydramine hydrochloride is a substance that relieves allergy symptoms like sneezing, itching, and runny nose and often causes drowsiness.
Esketamine
Esketamine is a fast-acting antidepressant substance used to relieve depression symptoms when other treatments haven't worked.
Esketamine Hydrochloride
Esketamine hydrochloride is a fast-acting substance used to treat severe depression when other treatments haven’t worked.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Allergan
Almus Max Strength Sleep Aid
Asda Night Time Sleep Aid

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Vienna
Division of General Psychiatry
Vienna, Austria
Sponsor: Medical University Of Vienna
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.