Oesophageal Adenocarcinoma
Oesophageal adenocarcinoma is a type of cancer that forms in the tissues of the esophagus, often linked to risk factors like acid reflux and obesity. Symptoms may include difficulty swallowing, weight loss, and chest pain.
Esophageal Adenocarcinoma: Metformin Treatment
We are studying whether metformin can enhance the immune response in patients with esophageal adenocarcinoma receiving chemoradiotherapy. This research may help improve treatment effectiveness and patient outcomes.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have diabetes (type 1 or type 2) and take medications for it, like metformin?
- Do you have serious heart problems, like a recent heart attack or severe heart failure?
- Are you currently pregnant, planning to become pregnant, or breastfeeding?
- Do you have severe kidney problems (creatinine clearance less than 30 ml/min)?
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Abmetfina Xr
Adimet
Adimet Xr
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Amsterdam UMC Stichting
medical oncology
Amstelveen, Netherlands
Dijklander Ziekenhuis
Medical oncology
Hoorn, Netherlands
Sponsor: Amsterdam UMC Stichting
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.