Fecal Incontinence: Botulinum Toxin Injections

We are studying how botulinum toxin injections may improve rectal movement in patients with fecal incontinence. The trial will also look at the treatment's effectiveness, quality of life, and tolerance after one month.

>2 years≤5 visitsConfirmation phase (III)No PlaceboStandard MedicinesOralInjectionGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Botox
Botox is a medicine used to relax muscles to reduce facial wrinkles and treat certain muscle- and nerve-related conditions.
Dulcolax
Dulcolax is a laxative medicine used to relieve constipation and help produce regular bowel movements.
Moviprep
Moviprep is a drink used to empty and clean the bowel before a colonoscopy or other bowel examination.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ascorbic Acid
Ascorbic acid is a substance that helps prevent vitamin C deficiency and supports immune function, collagen production, and iron absorption.
Bisacodyl
Bisacodyl is a substance that stimulates bowel movements to relieve constipation.
Botulinum Antitoxin Type A Ph. Eur.
Botulinum antitoxin type A is a substance that neutralizes botulinum toxin to treat and prevent worsening paralysis caused by botulism.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Actilax
Addex
Agaffin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Centre Hospitalier Universitaire Rouen
Digestive Physiology
Rouen, France
Sponsor: Centre Hospitalier Universitaire Rouen
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.