Follicular Lymphoma: Mosunetuzumab and Zanubrutinib Study

We are investigating a combination of two medications for patients with relapsed or refractory follicular lymphoma. The goal is to see if this treatment improves outcomes and safety compared to existing options.

>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesOralInjectionHematology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Brukinsa
Brukinsa is a cancer medicine used to treat certain types of blood cancer, including mantle cell lymphoma and Waldenström’s macroglobulinemia.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Mosunetuzumab
Mosunetuzumab is a lab-made antibody that helps the immune system target and kill certain B-cell lymphomas.
Zanubrutinib
Zanubrutinib is a substance that treats certain B‑cell blood cancers by blocking a protein that helps cancerous B cells grow.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Istituto Di Candiolo Fondazione Del Piemonte Per Loncologia IRCCS
Ematologia
Airali, Italy
Azienda Ospedaliero-Universitaria Ss Antonio E Biagio E Cesare Arrigo
SCDU Ematologia
Alessandria, Italy
Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I G M Lancisi G Salesi
Clinica di Ematologia
Ancona, Italy
Sponsor: Fondazione Italiana Linfomi Ets
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.