Gastric Cancer: Zolbetuximab with Pembrolizumab and Chemotherapy

We are studying a new treatment combination for adults with advanced gastric cancer to see if it works better than standard therapies. This trial is for patients with specific tumor markers.

Confirmation phase (III)Cost Reimbursement Partially Remote Investigational Medicines Oral InjectionGastroenterologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Capecitabine

Capecitabine is a chemotherapy medicine used to treat certain cancers, including breast and colon cancer.

Keytruda

Keytruda is a cancer medicine that helps the immune system find and fight tumor cells.

Vyloy

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Capecitabine

Capecitabine is a substance that helps stop certain cancers from growing, commonly used for breast and colorectal cancer.

Fluorouracil

Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.

Folinic Acid

Folinic acid is a substance that helps restore folate levels and protects healthy cells during certain chemotherapy treatments.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Asp8951

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Capecel

Capecitabin Al

Capecitabin Amarox

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Imelda

Gastroenterology

Hever, Belgium

UZ Leuven

Digestive Oncology

Heverlee, Belgium

Universitair Ziekenhuis Gent

Digestive Oncology

Ledeberg, Belgium

Sponsor: Astellas Pharma Global Development Inc.

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.