GD2 Positive Solid Cancers: GD2IL18CART Treatment

We are testing a new therapy called GD2IL18CART for patients with relapsed or hard-to-treat GD2 positive solid cancers. The study aims to assess safety, find the right dose, and evaluate how well the treatment works.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clemastine Tiofarma
Clemastine Tiofarma is a medicine used to relieve common allergy symptoms such as sneezing, runny nose, itching, and hives.
Levetiracetam
Levetiracetam is a medicine that helps prevent and control seizures in people with epilepsy.
Paracetamol
Paracetamol relieves pain and reduces fever for conditions like headaches, muscle aches, and colds.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anakinra
Anakinra is a substance that blocks interleukin-1 to reduce inflammation in conditions such as rheumatoid arthritis and other inflammatory disorders.
Buclizine Hydrochloride
Buclizine hydrochloride is an antihistamine substance used to prevent nausea, vomiting, and motion sickness.
Clemastine
Clemastine is an antihistamine substance used to relieve allergy symptoms such as sneezing, runny nose, and itchy, watery eyes.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Gd2il18cart

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitaetsklinikum Erlangen AöR
Medizinische Klinik 5 – Hämatologie und Internistische Onkologie
Erlangen, Germany
Universitaetsklinikum Erlangen AöR
Abteilung für Kinder- und Jugendmedizin
Erlangen, Germany
Universitaetsklinikum Essen AöR
Klinik für Kinderheilkunde III
Essen, Germany

Sponsor: Westfaelische Wilhelms Universitaet Muenster
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.