Generalized Myasthenia Gravis: DNTH103 Treatment Study

We are testing a new treatment called DNTH103 for adults with generalized myasthenia gravis. The study aims to evaluate its safety, tolerability, and effectiveness in managing symptoms.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bexsero
Bexsero is a vaccine that helps prevent group B bacterial infections that can cause severe brain or blood infections.
Nimenrix
Nimenrix is a vaccine that helps prevent meningitis and blood infections caused by meningococcal bacteria groups A, C, W, and Y.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Aluminium Hydroxide
Aluminium hydroxide is a substance that neutralizes stomach acid to relieve heartburn, indigestion, and acid-related discomfort.
N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated) Conjugated To Tetanus Toxoid
N. meningitidis group C polysaccharide conjugated to tetanus toxoid is a substance that helps prevent meningitis and blood infections from meningococcus.
N. Meningitidis Group C Polysaccharide
N. meningitidis group C polysaccharide is used in vaccines to stimulate immunity and help prevent infections caused by meningococcal group C bacteria.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Dnth103
Outer Membrane Vesicles (Omv) From Neisseria Meningitidis Group B Strain Nz98/254

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alk (Alutard Sq)
Alk-Depot Sq 802
Allergovit

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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MUDr. Eduard Minks, Ph.D. – Neurologie
Brno, Czechia
Fakultni Nemocnice Ostrava
Neurologicka klinika
Hlučín, Czechia
Rigshospitalet
Neuromuscular clinic and research unit, section 8077
Copenhagen, Denmark

Sponsor: Dianthus Therapeutics Inc.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.