Geographic Atrophy: JNJ-81201887 Treatment Study

We are examining the long-term safety and tolerability of JNJ-81201887 for people with geographic atrophy from age-related macular degeneration. This study follows participants from earlier trials to gather more information.

>2 years Efficacy phase (II)Post-Trial Drug Access Partially Remote Investigational Medicines Oral InjectionOphthalmology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Kenacort-A 40

Kenacort-A 40 is a steroid medicine used to reduce inflammation and relieve symptoms like swelling, pain, and allergic reactions.

Prednison Acis

Prednison Acis is a medicine that reduces inflammation and calms an overactive immune system for conditions like allergies, asthma, and autoimmune diseases.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Prednisone

Prednisone is a steroid substance that reduces inflammation and suppresses the immune system for conditions like allergies, asthma, and autoimmune disorders.

Triamcinolone Acetonide

Triamcinolone acetonide is a corticosteroid substance that reduces inflammation and treats allergic and inflammatory conditions like skin rashes, asthma, and joint swelling.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Jnj-81201887

Adeno-Associated Virus Serotype 2 Encoding Soluble Cd59

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adcortyl Intra-Articular / Intradermal Injection

Adcortyl Intra-Articular/Intradermal

Aldoderma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ziekenhuis Oost Limburg

Department of Ophthalmology

Genk, Belgium

UZ Leuven

Department of Ophthalmology

Heverlee, Belgium

Universiteit Gent

Department of Ophthalmology

Ledeberg, Belgium

Sponsor: Janssen - Cilag International

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.