Giant Cell Arteritis: Etanercept vs. Methotrexate

We are comparing two treatments, etanercept and methotrexate, to see which is more effective for patients with giant cell arteritis. The goal is to find out which treatment helps achieve remission and prevents complications better.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Enbrel
Enbrel is a medicine that helps reduce immune system–caused inflammation to treat rheumatoid arthritis, psoriatic arthritis, and some types of psoriasis.
Prednisone Eg
Prednisone Eg is a steroid medicine that reduces inflammation and treats allergic, autoimmune, and other inflammatory conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Etanercept
Etanercept is a substance that blocks a protein involved in inflammation to treat autoimmune conditions like rheumatoid arthritis and psoriasis.
Folic Acid
Folic acid is a B vitamin that helps make healthy red blood cells and prevent birth defects when taken during pregnancy.
Methotrexate
Methotrexate is a substance that slows rapid cell growth and calms the immune system to treat certain cancers and autoimmune conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Benepali
Brucorten
Cison

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Szpital Specjalistyczny Im.J.Dietla W Krakowie
Klinika Reumatologii i Immunologii
Kraków, Poland
Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicher
Centrum Wsparcia Badań Klinicznych
Ochota, Poland
Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji
Klinika Reumatologii, Chorób Tkanki Łącznej i Chorób Rzadkich
Ochota, Poland

Sponsor: Wojskowy Instytut Medyczny Panstwowy Instytut Badawczy
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.