Glioblastoma: Intraoperative Photodynamic Therapy with Pentalafen®

We are studying a new light-based treatment for adults with grade IV glioblastoma during surgery. The goal is to evaluate its safety and how well it works in reducing tumor response.

>2 years6-10 visitsSafety phase (I)Efficacy phase (II)No PlaceboStandard MedicinesOralNeurologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Pelafen

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Aminolevulinic Acid Hydrochloride
Aminolevulinic acid hydrochloride is a substance that makes abnormal cells glow under special light to help detect or treat certain skin lesions and tumors.
Dry Extract Of Pelargonium Root (Der 4-25:1)
Dry extract of Pelargonium root is a herbal substance used to relieve cough and support recovery from acute respiratory tract infections.
Extraction Solvent: Ethanol 11% (M/M)
Ethanol is a substance commonly used as a solvent and antiseptic for cleaning and preserving biological samples.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Centoreze
Diatussal
Dr. Böhm Infekt Grippal

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Centre Hospitalier Universitaire De Lille
Neurosurgery
Loos, France
Sponsor: Hemerion Therapeutics
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.