Glioblastoma Treatment: Lomustine and Temozolomide Study

We are studying whether a combination of lomustine and temozolomide improves survival for newly diagnosed glioblastoma patients with a specific genetic marker. This trial also looks at side effects and quality of life compared to standard treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Lomustine
Lomustine is a chemotherapy medicine used to treat certain cancers, especially brain tumors and some types of lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Lomustine
Lomustine is a cancer-fighting substance used to treat brain tumors and certain lymphomas by killing cancer cells.
Temozolomide
Temozolomide is a substance used in chemotherapy to treat certain types of brain tumors by slowing cancer cell growth.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Cecenu®
Lomustin (Ccnu) Medac
Lomustine Medac

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz
Department of Neurology and Division of Neuroradiology, Vascular and Interventional Radiology
Graz, Austria
Medizinische Universitaet Innsbruck
Department of Neurology, Medical University Innsbruck,
Innsbruck, Austria
Johannes Kepler University Linz
Kepleruniversitätsklinikum, Neuromed Campus, Konsiliardienst Innere Medizin und Neuroonkologie
Linz, Austria

Sponsor: Vaestra Goetalandsregionen
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.