Graft-Versus-Host Disease: Corticosteroids with ECP

We are studying whether adding extracorporeal photopheresis to corticosteroids helps patients with Grade II acute graft-versus-host disease after stem cell transplantation. This trial compares treatment outcomes and side effects between the two approaches.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cortancyl
Cortancyl is a steroid medicine used to reduce inflammation and treat allergies, asthma, and certain autoimmune or inflammatory conditions.
Noxafil
Noxafil is an antifungal medicine used to prevent and treat serious fungal infections, especially in people with weakened immune systems.
Posaconazole
Posaconazole is an antifungal medicine used to treat and prevent serious fungal infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Methoxsalen
Methoxsalen is a substance that makes skin sensitive to ultraviolet light to treat certain skin conditions like psoriasis and vitiligo.
Methylprednisolone
Methylprednisolone is a corticosteroid that reduces inflammation and calms an overactive immune system.
Methylprednisolone Hydrogen Succinate
Methylprednisolone hydrogen succinate is a corticosteroid substance that rapidly reduces inflammation and suppresses overactive immune responses.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Brucorten
Cison
Corten

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hopitaux Universitaires de Strasbourg - Hopital de la Robertsau
HEMATOLOGY
Bischheim, France
Institut De Cancerologie Strasbourg Europe
HEMATOLOGY
Eckbolsheim, France
CHRU De Nancy
HEMATOLOGY
Lamballe, France

Sponsor: CHRU De Nancy
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.