Grass Allergy: Vitamin D Enhanced Immunotherapy

We are studying whether combining intralymphatic immunotherapy with vitamin D helps improve allergy symptoms in people with moderate to severe grass allergies during pollen season.

>2 years 6-10 visits Efficacy phase (II)Confirmation phase (III)No Placebo Investigational Medicines Oral InjectionAllergology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Colecalciferol

Colecalciferol is a form of vitamin D used to prevent or treat low vitamin D levels and help maintain healthy bones.

Grazax

Grazax is a medicine in tablet form that helps reduce hay fever symptoms caused by grass pollen.

Natriumklorid Braun

Natriumklorid Braun is a sterile salt solution used to replace body fluids, rinse wounds, and prepare medicines for injection.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cholecalciferol Concentrate (Powder Form)

Cholecalciferol is a form of vitamin D used to raise and maintain healthy vitamin D levels for bone strength and immune support.

Colecalciferol

Colecalciferol is a substance that raises vitamin D levels to support healthy bones and maintain normal calcium balance.

Glycerol

Glycerol is a substance used to relieve constipation by drawing water into the bowel and softening stools.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Alutard

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Accrete D3

Accrete D3 One A Day

Acid Alendronic/Colecalciferol Accord

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Sodra Alvsborg Hospital Vastra Gotalandsregionen

Lungmottagningen

Borås, Sweden

Region Skane Skanes Universitetssjukhus

Allergimottagningen

Lund, Sweden

Region Oerebro Laen

Öron, näsa, hals mottagningen

Örebro, Sweden

Sponsor: Karolinska Institutet

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.