Graves' Ophthalmopathy: Diclofenac vs. Simvastatin

We are studying whether diclofenac or simvastatin can help patients with mild to moderate Graves' ophthalmopathy. The trial aims to assess the activity of the disease and its progression to more severe forms.

6-12 months≤5 visitsEfficacy phase (II)Confirmation phase (III)Standard MedicinesOralEndocrinologyOphthalmology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Diclofenac

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Diclofenac
Diclofenac is a substance that reduces pain and inflammation from conditions like arthritis and injuries.
Diclofenac Diethylamine
Diclofenac diethylamine is a topical anti-inflammatory substance used to relieve pain and swelling in muscles and joints.
Diclofenac Sodium
Diclofenac sodium is a substance that reduces pain and inflammation from arthritis and other muscle or joint problems.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Almiral
Artrimove
Bendol

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Skane Skanes Universitetssjukhus
Endokrin SUS
Dalby, Sweden
Sponsor: Region Skane
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.