Head and Neck Cancer: Cetuximab with Chemotherapy

We are studying a combination of cetuximab and chemotherapy followed by immunotherapy for patients with recurrent or metastatic head and neck cancer. The goal is to see if this treatment improves survival and response rates for those with a specific PD-L1 score.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Erbitux
Erbitux is a cancer treatment used to help slow the growth of certain colorectal and head and neck cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Avelumab
Avelumab is a substance that boosts the immune system to help the body recognize and attack certain types of cancer.
Cetuximab
Cetuximab is a substance that targets a protein on cancer cells to help slow or stop growth in colorectal and head and neck cancers.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Istituto Tumori Bari Giovanni Paolo II
Oncologia Medica
Bari, Italy
A. O. U. Policlinico Sant'Orsola Malpighi
Oncologia Medica
Bologna, Italy
RCCS Istituto delle Scienze Neruologiche di Bologna
Nervous system medical oncology
Bologna, Italy

Sponsor: Gruppo Oncologico Del Nord Ovest
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.