Head and Neck Cancer: Shortened Chemotherapy with Pembrolizumab

We are studying a shorter chemotherapy treatment combined with Pembrolizumab for patients with PD-L1-positive recurrent or metastatic head and neck cancer. The goal is to see if this approach is effective and safe compared to standard treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Carboplatine Accord
Carboplatine Accord is a chemotherapy medicine used to treat various types of cancer.
Cisplatine Accord
Cisplatine Accord is a chemotherapy medicine used to treat various types of cancer.
Fluorouracile Accord
Fluorouracile Accord is a chemotherapy medicine used to treat several types of cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Carboplatin
Carboplatin is a chemotherapy substance used to treat various cancers by damaging cancer cells and slowing tumor growth.
Cisplatin
Cisplatin is a substance used in chemotherapy to kill or stop the growth of cancer cells.
Fluorouracil
Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

5-Fluorouracil
5-Fluorouracil Ebewe
5-Fluorouracil Sandoz

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Sainte Catherine Institut Du Cancer Avignon-Provence
Radiation oncology
Avignon, France
Centre Jean Perrin
Medical oncology
Beaumont, France
Centre Hospitalier Universitaire De Bordeaux
Medical oncology
Bordeaux, France

Sponsor: Oncopole Claudius Regaud
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.