Heart Failure and Obesity: Weight Loss with Semaglutide

We are investigating whether weight loss using semaglutide is more effective than a calorie-restricted diet in improving physical performance for patients with heart failure and obesity. The study also looks at quality of life and heart health impacts from both weight loss methods.

1-2 years 11-15 visits Efficacy phase (II)No Placebo Partially Remote Investigational Medicines InjectionCardiologyDiabetologyEndocrinology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Wegovy

Wegovy is a prescription medicine used to help adults lose weight and keep it off.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Semaglutide

Semaglutide is a substance that helps lower blood sugar in people with type 2 diabetes and can also reduce appetite to aid weight loss.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Wegovy

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Ozempic

Rybelsus

Wegovy Flextouch

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hvidovre Hospital

Cardiology

Hvidovre, Denmark

Sponsor: Hvidovre Hospital

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.