Acute Heart Failure
Acute heart failure is a sudden worsening of the heart's ability to pump blood, leading to symptoms like shortness of breath, fatigue, and fluid retention.
Heart Failure: Engineered Heart Tissue Treatment
We are studying a new type of heart tissue made from stem cells for patients with severe heart failure. The goal is to see if it is safe and effective in improving heart function and related symptoms.
>2 years6-10 visitsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesCardiologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 80 years old?
- Do you have heart failure with reduced ejection fraction (HFrEF) or a history of heart problems?
- Are you pregnant or breastfeeding?
- Are you currently taking immunosuppressive drugs or have a history of unresolved cancer or HIV?
- Have you had a disabling stroke in the past?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Engineered Human Myocardium
Induced Pluripotent Stem Cells-Derived Cardiomyocytes and Stromal Cells
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Universitaetsmedizin Goettingen
Cardiology
Göttingen, Germany
Universitaetsklinikum Schleswig-Holstein AöR
Klinik für Herz- und thorakale Gefäßchirurgie
Lübeck, Germany
Sponsor: Universitaetsmedizin Goettingen
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.