Heart Failure with Reduced Ejection Fraction
Heart failure with reduced ejection fraction (HFrEF) is a condition where the heart cannot pump blood effectively, leading to symptoms like shortness of breath, fatigue, and fluid retention.
Heart Failure: JTT-861 Medication Study
We are evaluating a new medication, JTT-861, for individuals with heart failure with reduced ejection fraction. The study aims to see if it is safe and effective in improving heart function.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 30 and 85 years old?
- Do you have a diagnosis of heart failure that has been present for at least 90 days?
- Are you currently in New York Heart Association (NYHA) functional class II or III (meaning you have some limitations in physical activity)?
- Are you currently taking heart failure medications consistently for at least 4 weeks?
- Have you had a heart attack or unstable angina in the last 90 days?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Jtt-861
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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ASIMPKIP D-R Elena Docheva EOOD
Not applicable
Burgas, Bulgaria
Multi-profile Hospital for Active Treatment Heart and Brain EAD
First Department of Cardiology at the Cardiology Clinic
Pleven, Bulgaria
University Multiprofile Hospital For Active Treatment Dr. Georgi Stranski EAD
Clinic of cardiology
Pleven, Bulgaria
Sponsor: Akros Pharma Inc.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.