Heart Function Study: Dobutamine in ATTRwt Patients

We are investigating how different doses of dobutamine affect heart performance in patients with wild-type transthyretin amyloid cardiomyopathy. The study also looks at the safety of this treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dobutrex
Dobutrex is a medicine given through a vein to help a weak heart pump stronger during severe heart failure or heart-related shock.
Glukose Isotonisk Sad
Glukose Isotonisk Sad is an isotonic glucose solution given intravenously to provide fluids and quick energy for dehydration or low blood sugar.
Natriumklorid B. Braun
Natriumklorid B. Braun is a sterile saline solution used to replace body fluids and salts, hydrate patients, and flush wounds or medical lines.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dobutamine
Dobutamine is a substance that helps the heart contract more strongly to improve blood flow in acute heart failure or low cardiac output.
Dobutamine Hydrochloride
Dobutamine hydrochloride is a substance that strengthens heart pumping to improve blood flow in people with severe heart failure or shock.
Glucose Monohydrate
Glucose monohydrate is a form of sugar used to provide quick energy and to raise low blood sugar levels.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Addex Natriumklorid
Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Midtjylland
Cardiology
Århus, Denmark
Sponsor: Region Midtjylland
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.