Heart Procedure: Comparing Blood Thinners

We are studying how two different blood-thinning treatments affect blood clotting in patients undergoing closure of heart defects. This may help us understand which treatment is safer and more effective after the procedure.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Plavix
Plavix is a medicine that helps prevent harmful blood clots and lowers the risk of heart attack and stroke.
Xarelto
Xarelto is a medicine that helps prevent and treat blood clots and reduce stroke risk in people with an irregular heartbeat.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acetylsalicylic Acid
Acetylsalicylic acid is a substance that reduces pain, fever, and inflammation and can help prevent blood clots.
Caffeine Citrate
Caffeine citrate is a stimulant used to help premature infants breathe more regularly by treating breathing pauses.
Clopidogrel
Clopidogrel is a substance that helps prevent blood clots by stopping platelets from sticking together, lowering the risk of heart attack and stroke.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aban
Aclop
Adagrel

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Sint Antonius Ziekenhuis Stichting
Cardiology
Nieuwegein, Netherlands
Sponsor: Sint Antonius Ziekenhuis Stichting
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.