Pancreatic Cancer
Pancreatic cancer is a type of cancer that begins in the tissues of the pancreas, often leading to symptoms like abdominal pain, weight loss, and jaundice.
HER2 Mutated Solid Tumors: Sevabertinib Study
We are studying how well sevabertinib tablets work and their safety for patients with solid tumors that have HER2 mutations. This research may help improve treatment options for these patients.
6-12 monthsEfficacy phase (II)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesOralInternal MedicineOncology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Urothelial Carcinoma
Urothelial carcinoma is a cancer that affects the bladder and urinary tract, commonly presenting with symptoms such as blood in urine and frequent urination.
Gallbladder Cancer
Gallbladder cancer is a rare type of cancer that forms in the gallbladder, often causing symptoms like abdominal pain and jaundice.
Breast Cancer
Breast cancer is a common cancer that forms in the cells of the breasts, with symptoms including lumps in the breast, changes in breast shape, and discharge from the nipple.
Endometrial Cancer
Endometrial cancer is a type of cancer that begins in the lining of the uterus, often presenting with symptoms like abnormal bleeding and pelvic pain.
Ovarian Cancer
Ovarian cancer is a cancer that begins in the ovaries, with symptoms that may include abdominal bloating, pelvic pain, and changes in bowel habits.
Bladder Cancer
Bladder cancer is a type of cancer that starts in the bladder, often causing symptoms like blood in urine and frequent urination.
Colorectal Cancer
Colorectal cancer is a cancer that starts in the colon or rectum, with symptoms including changes in bowel habits, abdominal discomfort, and blood in stool.
Cervical Cancer
Cervical cancer is a type of cancer that occurs in the cervix, often presenting with symptoms like abnormal bleeding and pelvic pain.
Esophageal Cancer
Esophageal cancer is a cancer that occurs in the esophagus, with symptoms that may include difficulty swallowing, weight loss, and chest pain.
Gastric Cancer
Gastric cancer is a type of cancer that occurs in the stomach, often causing symptoms like indigestion, stomach pain, and nausea.
Sarcoma
Sarcoma is a type of cancer that arises from connective tissues, with symptoms that may include lumps and swelling in the affected area.
Malignant Solid Tumor
Malignant solid tumors are cancers that form solid masses in various tissues, often leading to symptoms depending on their location.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Do you have a solid tumor cancer like breast cancer, colorectal cancer, or cervical cancer?
- Have you received standard treatment for your cancer or have no other treatment options?
- Do you have an active HER2 mutation (a specific change in your cancer's genes)?
- Do you have any severe health problems that are not under control?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Bay 2927088
Sevabertinib
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Agrocia
Alocutan
Alocutan Forte
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Region Midtjylland
Oncology
Århus, Denmark
Rigshospitalet
Oncology
Copenhagen, Denmark
Odense University Hospital
Oncology
Odense, Denmark
Sponsor: Bayer AG
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.