HER2-Positive Breast Cancer: Trastuzumab and Pertuzumab Study

We are exploring a new treatment approach for patients with HER2-positive unresectable locally advanced or metastatic breast cancer. This study aims to see how well this treatment works and its safety compared to existing options.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Herceptin
Herceptin is a medicine used to treat certain types of breast and stomach cancer.
Phesgo
Phesgo is a medication used to treat HER2-positive breast cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Pertuzumab
Pertuzumab is a targeted antibody used to treat HER2-positive breast cancer by blocking signals that help tumor cells grow.
Trastuzumab
Trastuzumab is a substance that targets HER2 proteins to treat certain HER2-positive breast and stomach cancers.
Trastuzumab Deruxtecan
Trastuzumab deruxtecan is a targeted cancer treatment that attacks tumors with high HER2 protein levels.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Enhertu

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Herwenda
Herwenda
Herzuma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hopital Tenon
Medical Oncology
Bagnolet, France
Assistance Publique Hopitaux De Paris
Medical Oncology
Issy-les-Moulineaux, France
Institut Paoli-Calmettes
Medical Oncology
Marseille, France

Sponsor: Medica Scientia Innovation Research S.L.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.