HER2-Positive Oligo-Metastatic Breast Cancer: T-DXd Treatment Study

We are investigating how well T-DXd works in combination with other treatments for patients with HER2-positive oligo-metastatic breast cancer. The study will also look at safety and how it affects cancer markers in the blood.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Trastuzumab Deruxtecan
Trastuzumab deruxtecan is a targeted cancer treatment that attacks tumors with high HER2 protein levels.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ds-8201a

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut Gustave Roussy
Departement of Medicine
Villejuif, France
Fondazione IRCCS Istituto Nazionale Dei Tumori
Oncologia Medica 1
Milan, Italy
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
MOD
Amstelveen, Netherlands

Sponsor: Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.