High Cholesterol
High Cholesterol, or Hypercholesterolemia, is a condition where there are elevated levels of cholesterol in the blood, which can increase the risk of heart disease and stroke.
High 'Bad' Cholesterol: AZD0780 Study
We are investigating how well AZD0780 works for adults with high LDL cholesterol and heart disease or at risk for it. The goal is to see if it can lower cholesterol levels more effectively than a placebo.
1-2 years6-10 visitsConfirmation phase (III)Investigational MedicinesOralCardiologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease is a condition where arteries become narrowed and hardened due to cholesterol and other substances, leading to reduced blood flow and increased risk of heart attacks and strokes.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have a history of heart disease, such as a heart attack or stroke?
- Do you have diabetes or high blood sugar problems?
- Are you currently taking cholesterol-lowering medications like Lipitor (atorvastatin) or Crestor (rosuvastatin)?
- Have you had any major kidney problems, such as severe kidney disease?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Azd0780
Laroprovstat
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Medical Center Medtech Services Ltd.
Haskovo, Bulgaria
Diagnostic Consultative Center Sveti Georgi EOOD
Plovdiv, Bulgaria
University Multiprofile Hospital For Active Treatment Saint Georgi EAD
Cardiology clinic
Plovdiv, Bulgaria
Sponsor: AstraZeneca AB
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.