Glioma
Glioma is a type of tumor that occurs in the brain and spinal cord, originating from glial cells, which support and protect nerve cells. Symptoms can vary widely depending on the tumor's location and size.
High-Grade Glioma: Abemaciclib with Temozolomide
We are studying whether adding abemaciclib to temozolomide helps children and young adults with newly diagnosed high-grade glioma after radiotherapy. This trial compares the combination treatment to temozolomide alone.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 3 and 75 years old?
- Do you have high-grade glioma (a type of brain tumor)?
- Have you had prior treatment for your glioma, like surgery or radiotherapy?
- Are you currently pregnant or breastfeeding?
- Do you have any serious medical conditions, like a severe infection or heart disease?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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UZ Leuven
Pediatric hemato-oncology department
Heverlee, Belgium
Universitair Ziekenhuis Gent
Pediatric hemato- oncology department
Ledeberg, Belgium
Centre Hospitalier Regional De La Citadelle
Pediatric hemato-oncology department
Liège, Belgium
Sponsor: Eli Lilly & Co.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.