High-Risk Neuroblastoma: Naxitamab and GM-CSF Treatment

We are studying a new treatment combining naxitamab and GM-CSF for children with high-risk neuroblastoma who have not responded to prior therapies. The trial aims to assess how well this treatment works and its safety.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Aldesleukin
Aldesleukin is a synthetic form of a natural immune-signaling protein that boosts the body's immune response to help treat certain cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Humanized IgG1 Monoclonal Antibody Against GD2
Naxitamab
Sargramostim

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Rigshospitalet
Børneonkologisk afsnit, BørneUngeKlinikken
Copenhagen, Denmark
Assistance Publique Hopitaux De Marseille
Hématologie-Oncologie Pédiatrique
Marseille, France
University Medical Center Hamburg-Eppendorf
Abteilung für Pädiatrische Hämatologie und Onkologie
Hamburg, Germany

Sponsor: Y-mAbs Therapeutics A/S
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.