Hip Replacement Pain Management: Néfopam Study

We are studying the effects of néfopam on pain relief after hip replacement surgery. This trial compares its use against a placebo to see if it helps reduce the need for morphine and improves recovery.

6-12 monthsConfirmation phase (III)Standard MedicinesInjectionInternal MedicineOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Acupan
Acupan is a pain medicine used to relieve moderate to severe pain, often after injury or surgery.
Chlorure De Sodium Baxter
Chlorure De Sodium Baxter is a sterile salt solution used to replace lost fluids and help keep patients hydrated during medical care.
Nefopam
Nefopam is a medicine used to relieve moderate pain, often after surgery or injury.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Nefopam
Nefopam is a substance that relieves moderate to severe pain by acting on the central nervous system.
Nefopam Hydrochloride
Nefopam hydrochloride is a pain-relieving substance used to treat moderate acute pain by acting on the central nervous system.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Addex Natriumklorid
Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Blois Simone Veil
Anesthésie-réanimation
Blois, France
Les Hopitaux De Chartres
Anesthésie-réanimation
Chartres, France
Centre Hospitalier Universitaire D Angers
Anesthésie-réanimation
Ivry-sur-Seine, France
Sponsor: Centre Hospitalier Regional Universitaire De Tours
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.