HIV-1 Treatment: High-Dose Antiretroviral Drugs

We are studying whether high doses of antiretroviral drugs can reduce the hidden HIV-1 reservoir in people living with HIV. This trial will also assess the safety and effects of the treatment on immune markers.

6-12 monthsEfficacy phase (II)No PlaceboStandard MedicinesOralInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Celsentri
Celsentri is a medicine used to treat HIV infection by preventing the virus from entering certain immune cells.
Lamivudina Normon
Lamivudina Normon is a medicine used to treat HIV infection and chronic hepatitis B by helping control the viruses.
Maraviroc
Maraviroc is a medicine used to treat HIV infection by preventing the virus from entering certain immune cells.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dolutegravir
Dolutegravir is a substance that helps control HIV infection by blocking the virus from inserting its genetic material into human cells.
Dolutegravir Sodium
Dolutegravir sodium is a substance that helps control HIV by blocking the virus from inserting its genetic material into human cells.
Lamivudine
Lamivudine is a substance that helps treat HIV and hepatitis B by stopping the viruses from multiplying.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Delstrigo
Dovato
Epivir

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ramon y Cajal University Hospital
infectious diseases service
Chamartín, Spain
Hospital Universitario 12 De Octubre
HIV Infection Unit
Torrejón de Ardoz, Spain
Sponsor: Fundacion Para La Investigacion Biomedica Del Hospital Universitario Ramon Y Cajal
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.