HIV and HBV Co-Infection: Antiviral Treatment Strategies

We are studying two treatment reduction strategies for patients co-infected with HIV-1 and HBV to see how safely they can manage their viral infections. The trial will also look at the impact on quality of life and any potential side effects.

>2 years11-15 visitsEfficacy phase (II)No PlaceboStandard MedicinesOralHepatologyInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Epivir
Epivir is a medicine used with other drugs to help control HIV and lower the amount of virus in the body.
Norvir
Norvir is a medicine used to treat HIV infection and boost other HIV drugs' effectiveness.
Prezista
Prezista is a medicine used to treat HIV infection by helping to control the virus.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Darunavir
Darunavir is a substance that helps control HIV by blocking a viral enzyme needed for the virus to reproduce.
Dolutegravir
Dolutegravir is a substance that helps control HIV infection by blocking the virus from inserting its genetic material into human cells.
Dolutegravir Sodium
Dolutegravir sodium is a substance that helps control HIV by blocking the virus from inserting its genetic material into human cells.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Darunasta
Darunavir "sandoz"
Darunavir 400 Mg Filmcoated Tablets

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hopital Tenon
Service des Maladies Infectieuses
Bagnolet, France
Centre Hospitalier Universitaire De Toulouse
Service des Maladies Infectieuses et Tropicales
Blagnac, France
Assistance Publique Hopitaux De Paris
Service des Maladies Infectieuses et Tropicales
Bondy, France
Sponsor: Inserm
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.