HIV-1 Infection
HIV-1 is a type of human immunodeficiency virus that attacks the immune system, making it harder for the body to fight off infections and diseases. If left untreated, it can lead to acquired immunodeficiency syndrome (AIDS).
HIV Research: Topiramate Treatment
We are investigating whether topiramate can help activate hidden HIV in people on antiretroviral therapy. The study also examines the safety of this medication and how various factors may influence its effects.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Do you have documented HIV-1, subtype B or C?
- Have you been on HIV treatment (ART) for at least 2 years?
- Is your CD4+ T cell count 200 cells/mm3 or higher?
- Have you had any major medical condition that required hospitalization in the past 4 weeks?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Internal Medicine-Infectious Diseases
Rotterdam, Netherlands
Sponsor: Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.