HIV Treatment: Combination Therapy Study

We are investigating a combination of three drugs to see if they can help reactivate HIV in people living with the virus. This study aims to understand the safety and effectiveness of these treatments.

≤3 months≤5 visitsEfficacy phase (II)No PlaceboCost ReimbursementPartially RemoteStandard MedicinesOralInfectious DiseasesInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Lenalidomide
Lenalidomide is a medicine used to treat certain blood cancers and bone marrow disorders, including multiple myeloma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Lenalidomide
Lenalidomide is a substance that helps treat certain blood cancers by affecting the immune system to stop cancer growth.
Panobinostat
Panobinostat is a substance used to treat certain cancers by stopping cancer cell growth, commonly for advanced multiple myeloma.
Pyrimethamine
Pyrimethamine is a substance that treats and prevents certain parasitic infections like toxoplasmosis and malaria by stopping parasite growth.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

7,5 Mg Stada
Cortedal
Ferulinor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Amsterdam UMC
Internal medicine
Amstelveen, Netherlands
Universitair Medisch Centrum Utrecht
Internal medicine
De Bilt, Netherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Internal medicine
Rotterdam, Netherlands
Sponsor: Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.