HIV Treatment Comparison: Doravirine vs. Dolutegravir

We are studying whether doravirine is as effective as dolutegravir for people newly diagnosed with HIV-1. The trial also examines potential side effects and health changes over time.

>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesOralInfectious DiseasesInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Delstrigo
Delstrigo is a medicine used to treat HIV infection in adults by helping to control the virus.
Tivicay
Tivicay is a medicine used to treat HIV infection by helping stop the virus from multiplying in the body.
Truvada
Truvada is a medicine used to treat and reduce the risk of HIV infection.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dolutegravir
Dolutegravir is a substance that helps control HIV infection by blocking the virus from inserting its genetic material into human cells.
Dolutegravir Sodium
Dolutegravir sodium is a substance that helps control HIV by blocking the virus from inserting its genetic material into human cells.
Doravirine
Doravirine is a substance that helps control HIV infection by preventing the virus from multiplying.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Atrilesto
Dovato
Efatriten

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hôpital Saint André
Service des maladies infectieuses et tropicales
Bordeaux, France
Pellegrin Hospital
Service des maladies infectieuses et tropicales
Bordeaux, France
Hôpital La Colombière
Service des maladies infectieuses et tropicales
Montpellier, France
Sponsor: Inserm
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.