Hodgkin Lymphoma: A2VD vs. ABVD Treatment Study

We are comparing two treatment options for patients with untreated early-stage Hodgkin lymphoma to see which may improve survival and reduce side effects. This study uses advanced imaging techniques to guide treatment decisions.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Adcetris
Adcetris is a cancer medicine used to treat certain types of lymphoma, cancers that affect the lymphatic (immune) system.
Bleomycin
Bleomycin is a chemotherapy medicine used to treat certain types of cancer.
Dacarbazine Medac
Dacarbazine Medac is a chemotherapy medicine used to treat certain types of cancer, including melanoma and Hodgkin lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bleomycin
Bleomycin is a substance used in chemotherapy to kill or stop the growth of cancer cells.
Brentuximab Vedotin
Brentuximab vedotin is a substance used to treat certain types of lymphoma by targeting cancer cells with the CD30 protein.
Dacarbazine
Dacarbazine is a chemotherapy substance used to treat certain cancers, including melanoma and Hodgkin lymphoma.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Accofil
Bellon
Bleo-Cell

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ziekenhuis Aan De Stroom
Hematology
Antwerpen, Belgium
UZ Leuven
oncology
Heverlee, Belgium
Az Delta
hematology
Rumbeke, Belgium

Sponsor: University College London
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.