Hodgkin's Lymphoma: Atezolizumab and BEGEV Treatment

We are studying a new combination treatment for patients with relapsed or refractory Hodgkin's lymphoma to see if it helps improve response rates before stem-cell transplantation. This trial will also evaluate the safety and tolerability of this treatment approach.

>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboStandard MedicinesInjectionHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bendamustine
Bendamustine is a chemotherapy medicine used to treat certain blood cancers, such as lymphoma and some types of leukemia.
Bendamustine Hydrochloride
Bendamustine Hydrochloride is a chemotherapy medicine used to treat certain blood cancers, such as chronic lymphocytic leukemia and non-Hodgkin lymphoma.
Vinorelbine
Vinorelbine is a chemotherapy medicine used to treat certain cancers, most commonly lung and breast cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Atezolizumab
Atezolizumab is a substance that helps the immune system recognize and attack certain cancers by blocking a protein called PD-L1.
Bendamustine
Bendamustine is a substance used to treat certain cancers, especially non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Bendamustine Hydrochloride
Bendamustine hydrochloride is a chemotherapy substance used to treat certain blood cancers by killing cancer cells.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Benda Nc
Benda Nc
Bendamedac

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azienda Ospedaliero-Universitaria Ss.Antonio E Biagio E C.Arrigo Alessandria
S.C. Ematologia
Alessandria, Italy
Azienda Sanitaria Locale Della Provincia Di Barletta Andria Trani
Ematologia - Ospedale "Monsignor Raffaele Dimiccoli"
Andria, Italy
AORN San Giuseppe Moscati Avellino
S.C. Ematologia e Trapianto emopoietico
Avellino, Italy
Sponsor: Fondazione Italiana Linfomi Ets
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.