Hydrocortisone Treatment in Pancreatoduodenectomy Surgery

We are studying whether hydrocortisone infusions can help reduce complications after pancreatoduodenectomy surgery. This trial compares the effects of hydrocortisone to a placebo in patients undergoing this procedure.

>2 years≤5 visitsEfficacy phase (II)Confirmation phase (III)Partially RemoteStandard MedicinesInjectionGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Hydrocortison Pfizer
Hydrocortison Pfizer is a medicine used to relieve skin inflammation, redness, and itching from eczema, rashes, or allergic reactions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Hydrocortisone
Hydrocortisone is a substance that reduces inflammation and calms overactive immune responses for conditions like rashes, allergies, and eczema.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abix
Acecort
Actocortina

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Charite Universitaetsmedizin Berlin KöR
Chirurgische Klinik
Berlin, Germany
St. Josef-Hospital
Klinik für Allgemein- und Viszeralchirurgie
Bochum, Germany
Medical Center - University Of Freiburg
Klinik für Allgemein- und Viszeralchirurgie
Freiburg, Germany
Sponsor: Universitaetsklinikum Schleswig-Holstein AöR
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.