Hydroxychloroquine for Mastocytosis Symptoms

We are studying whether hydroxychloroquine can help reduce itching and flushing in patients with isolated cutaneous mastocytosis or indolent systemic mastocytosis with skin involvement. The trial also looks at other symptoms and how well patients tolerate the treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Plaquenil
Plaquenil is a medicine used to treat malaria and certain autoimmune conditions like lupus and rheumatoid arthritis.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Hydroxychloroquine Sulfate
Hydroxychloroquine sulfate is a substance used to prevent or treat malaria and to help control autoimmune conditions such as lupus and rheumatoid arthritis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Autokila
Dolquine
Duplaxil

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Montpellier
Centre de Compétences des Maladies Rares Dermatologiques et Génétiques
Montpellier, France
Centre Hospitalier Universitaire De Toulouse
Centre de référence des mastocytoses
Ramonville-Saint-Agne, France
Sponsor: Centre Hospitalier Universitaire De Toulouse
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.