Polymyositis
Polymyositis is a rare inflammatory disease that causes muscle weakness, particularly in the muscles closest to the trunk of the body. It can lead to difficulty in performing daily activities.
Idiopathic Inflammatory Myopathies: Upadacitinib Study
We are testing whether Upadacitinib can help patients with idiopathic inflammatory myopathies maintain stable disease after stopping IVIG treatment. The study compares its effects to a placebo over 16 weeks.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Dermatomyositis
Dermatomyositis is a rare inflammatory condition characterized by muscle weakness and a distinctive skin rash. It affects both adults and children and can impact daily functioning.
Antisynthetase Syndrome
Antisynthetase syndrome is a rare autoimmune condition that involves muscle inflammation and can also affect the lungs, leading to symptoms like muscle weakness and respiratory issues.
Overlap Myositis
Overlap myositis refers to a condition where features of myositis overlap with other autoimmune diseases, leading to muscle weakness and other systemic symptoms.
Immune-mediated Necrotizing Myopathy
Immune-mediated necrotizing myopathy is a rare condition characterized by severe muscle weakness and damage due to an autoimmune response, often requiring prompt medical attention.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 65 years old?
- Do you have a diagnosis of idiopathic inflammatory myopathies (IIM) like polymyositis or dermatomyositis?
- Are you currently pregnant or breastfeeding?
- Are you taking any immunosuppressive medications or corticosteroids like prednisone?
- Have you had any major surgery in the past 8 weeks?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Medical University Of Vienna
Division of Rheumatology
Vienna, Austria
Sponsor: Medical University Of Vienna
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.