Ifinatamab Deruxtecan for Metastatic Prostate Cancer

We are studying ifinatamab deruxtecan to see if it is safe and effective for men with metastatic castration-resistant prostate cancer. This trial will help us understand how well it works compared to other treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Abiraterone
Abiraterone is a medicine used to treat prostate cancer by lowering male hormones that can make the cancer grow.
Hydrocortisone
Hydrocortisone is a steroid medicine used to reduce inflammation and treat skin rashes, eczema, allergic reactions, and some hormone problems.
Ovastat

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abiraterone
Abiraterone is a substance that reduces testosterone production to help manage advanced prostate cancer.
Abiraterone Acetate
Abiraterone acetate is a substance that lowers the body's male hormones to slow the growth of prostate cancer.
Betamethasone Sodium Phosphate
Betamethasone sodium phosphate is a corticosteroid substance that reduces inflammation and suppresses immune reactions in allergic, inflammatory, and skin conditions.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ifinatamab Deruxtecan

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut De Cancerologie De L Ouest
Oncologie médicale
Angers, France
Centre Hospitalier De La Cote Basque
Oncologie médicale
Bayonne, France
Institut Bergonie
Oncologie médicale
Bordeaux, France

Sponsor: Merck Sharp & Dohme LLC
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.