Urothelial Carcinoma
Urothelial carcinoma is a type of cancer that begins in the urothelial cells lining the bladder and other parts of the urinary tract. It can cause symptoms like blood in urine, frequent urination, and pain during urination.
IMC-F106C for Advanced PRAME-Positive Cancers
We are studying a new treatment called IMC-F106C for individuals with advanced PRAME-positive cancers. The trial aims to assess its safety and effectiveness, both alone and with other cancer therapies.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Non-Small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, which can develop in different parts of the lungs. Symptoms may include a persistent cough, chest pain, and difficulty breathing.
Ovarian Carcinoma
Ovarian carcinoma is a type of cancer that begins in the ovaries. It often goes undetected until it has spread within the pelvis and abdomen, leading to symptoms like abdominal bloating, pain, and changes in bowel habits.
Synovial Sarcoma
Synovial sarcoma is a rare type of cancer that typically occurs in the soft tissues around joints, particularly in the arms and legs. Symptoms may include swelling and pain near the affected joint.
Uterine Carcinoma
Uterine carcinoma is a cancer that starts in the lining of the uterus. Common symptoms include abnormal vaginal bleeding, pelvic pain, and changes in menstrual cycles.
Malignant Melanoma of Skin
Malignant melanoma is a serious form of skin cancer that develops from melanocytes, the cells that produce pigment in the skin. Symptoms may include changes in existing moles or the appearance of new, unusual moles.
Triple Negative Breast Cancer
Triple negative breast cancer is a type of breast cancer that does not have any of the three common receptors known to fuel most breast cancer growth. Symptoms may include a lump in the breast, changes in breast shape, and discharge from the nipple.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Do you have any ongoing serious lung problems or breathing issues?
- Do you have any serious heart problems or heart function issues?
- Have you had any bowel problems like obstruction or perforation in the last 3 months?
- Have you had any major side effects from cancer treatment that were severe?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Brenetafusp
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Abutrax
Alimta
Apexelsin
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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SCRI CCCIT Ges.m.b.H.
Universitätsklinik für Innere Medizin III der PMU
Salzburg, Austria
UZ Brussel
Medical Oncology
Ganshoren, Belgium
UZ Leuven
Medical Oncology
Heverlee, Belgium
Sponsor: Immunocore Limited
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.