Immune Thrombocytopenia: Avatrombopag vs. Rituximab

We are comparing the effectiveness of Avatrombopag and Rituximab in adults with ITP who did not respond to corticosteroids. The study aims to see which treatment better improves health-related quality of life and reduces fatigue.

1-2 years Confirmation phase (III)No Placebo Standard Medicines Oral InjectionHematologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Eltrombopag

Eltrombopag is a medicine that helps increase blood platelet counts in people with certain conditions that cause low platelets.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Avatrombopag Maleate

Avatrombopag maleate is a substance that helps raise platelet levels by stimulating platelet production to treat low platelet counts.

Eltrombopag

Eltrombopag is a substance that increases platelet production to help manage low platelet counts.

Rituximab

Rituximab is a substance that targets and reduces B cells, a type of white blood cell, to treat some blood cancers and autoimmune conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Elrevolan

Eltrombgopa Glenmark

Eltrombopag +pharma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Helse Bergen HF

Avdeling Medisin, Hematologisk

Bergen, Norway

Nordlandssykehuset HF

Hematologisk avdeling

Bodø, Norway

Ostfold Hospital Trust

Thrombosis and hematologisk avdeling

Fredrikstad, Norway

Sponsor: Ostfold Hospital Trust

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.