Immune Thrombocytopenia: New Combination Therapy

We are studying a new treatment combining four medications for patients with immune thrombocytopenia. The trial will evaluate its effectiveness, safety, and impact on quality of life.

6-10 visits Efficacy phase (II)No Placebo Standard Medicines Oral InjectionHematologyInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Doptelet

Doptelet is a medicine that raises low platelet counts to reduce bleeding risk in adults with certain platelet disorders or before medical procedures.

Eltrombopag

Eltrombopag is a medicine that helps increase blood platelet counts in people with certain conditions that cause low platelets.

Nplate

Nplate is a medicine used to increase low platelet counts in people with immune-related conditions that can cause excessive bleeding.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Avatrombopag Maleate

Avatrombopag maleate is a substance that helps raise platelet levels by stimulating platelet production to treat low platelet counts.

Ciclosporin

Ciclosporin is a substance that suppresses the immune system to prevent organ transplant rejection and treat autoimmune conditions.

Eltrombopag

Eltrombopag is a substance that increases platelet production to help manage low platelet counts.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Elrevolan

Eltrombgopa Glenmark

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fakultni Nemocnice Hradec Kralove

IV. interní hematologická klinika

Hradec Králové, Czechia

Sponsor: Fakultni Nemocnice Hradec Kralove

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.