INBRX-109 for Advanced Solid Tumors, Including Sarcomas

We are studying a new treatment, INBRX-109, in combination with chemotherapy for adults and adolescents with advanced solid tumors like Ewing sarcoma and colorectal cancer. The goal is to assess its safety and how well it works compared to current treatments.

1-2 years≤5 visitsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOralInjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Temodal
Temodal is a chemotherapy medicine used to treat certain brain tumors, helping to slow tumor growth.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

1
3-Butylene Glycol
3-Butylene Glycol is a substance that helps retain moisture and acts as a solvent in skincare and topical formulations.
Cinchocaine Hydrochloride
Cinchocaine hydrochloride is a local anesthetic used to numb skin and mucous membranes to relieve pain and itching.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Temodal
Campto
Ozekibart

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Advecit
Blastomat
Nogron

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Leon Berard
Medical Oncology
Meyzieu, France
Institut Gustave Roussy
Children and adolescent oncology department
Villejuif, France
Istituto Di Candiolo Fondazione Del Piemonte Per Loncologia IRCCS
Oncology
Airali, Italy
Sponsor: Inhibrx Inc.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.