Infection Prevention in Joint Replacement: PREVENT-iT Study

We are studying whether different irrigation solutions and local vancomycin can lower the risk of infections after hip or knee joint replacement surgeries. This research aims to improve patient outcomes and reduce the need for additional surgeries.

Confirmation phase (III)Standard MedicinesInfectious DiseasesOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Benzalkonium Chloride
Benzalkonium chloride is a disinfectant and preservative used to kill germs on surfaces and in some eye, nasal, and topical products.
Benzyl Alcohol
Benzyl alcohol is a preservative and solvent used to prevent bacterial growth and help other ingredients work in injectable and topical products.
Chlorhexidine
Chlorhexidine is an antiseptic substance used to kill germs on skin and in the mouth to help prevent or treat infections.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Hospital Universitari Vall D Hebron
Orthopedic Surgery and Traumatology Service (Hip Unit)
Barcelona, Spain
Hospital Universitari Vall D Hebron
Orthopedic Surgery and Traumatology Service (Knee Unit)
Barcelona, Spain
Hospital Clinic De Barcelona
Orthopedic Surgery and Traumatology Service (Knee Unit)
El Altet, Spain
Sponsor: Hamilton Health Sciences Corporation
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.