Infectious Pulmonary Endotheliopathy: Iloprost Infusion Study

We are investigating whether a continuous infusion of iloprost can help reduce the risk of death in mechanically ventilated patients with infectious pulmonary issues. This study compares the treatment to a placebo to assess its effectiveness.

>2 years≤5 visitsEfficacy phase (II)Standard MedicinesInjectionInternal MedicinePulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ilomedin
Ilomedin is a medicine that widens blood vessels to treat high blood pressure in the lungs.
Natriumklorid B. Braun
Natriumklorid B. Braun is a sterile saline solution used to replace body fluids and salts, hydrate patients, and flush wounds or medical lines.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Iloprost Trometamol
Iloprost trometamol is a substance that widens blood vessels and improves blood flow, often used for pulmonary arterial hypertension and circulation problems.
Natrium Chloratum D12
Natrium Chloratum D12 is a highly diluted sodium chloride used in homeopathy to address various mild physical and emotional symptoms.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Addex Natriumklorid
Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Hovedstaden
Intensive care unit
Frederiksberg, Denmark
Nordsjaellands Hospital
Intensive care unit
Hillerød, Denmark
Region Hovedstaden
Intensive care unit
Hvidovre, Denmark
Sponsor: Rigshospitalet
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.