Inhaled Sevoflurane for Sedation in Critically Ill Patients

We are studying whether inhaled sevoflurane improves breathing and safety in ICU patients at risk for ARDS compared to standard sedation methods. This research may help us understand better sedation options for these vulnerable patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Diprivan-20
Diprivan-20 is a medicine given through a vein to make people sleep during surgery or for short-term medical procedures.
Hypnovel
Hypnovel is a medicine used to help patients relax, become drowsy, or sleep before and during medical procedures.
Nimbex
Nimbex is a medicine used to relax muscles during surgery or when a patient needs help breathing with a ventilator.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cisatracurium
Cisatracurium is a substance that temporarily relaxes skeletal muscles to allow surgery or mechanical ventilation.
Cisatracurium Besilate
Cisatracurium besilate is a substance that temporarily relaxes muscles to help with breathing support and during surgeries.
Dexmedetomidine
Dexmedetomidine is a sedative substance used to calm patients and reduce anxiety and pain during surgery or in intensive care.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Anesia
Anesia Baxter
Buccolam

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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University Hospital Of Clermont-Ferrand
Anesthésie-réanimation
Clermont-Ferrand, France
Sponsor: CHU Gabriel-Montpied
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.