Insomnia in Psychiatric Patients: Melatonin vs. Quetiapine

We are studying whether melatonin or low-dose quetiapine can improve sleep and overall well-being in patients with psychiatric disorders and chronic insomnia. This trial compares these treatments to a placebo to find the most effective option.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Melatonin Orifarm
Melatonin Orifarm helps people fall asleep and cope with jet lag.
Quetiapine Sandoz
Quetiapine Sandoz is a medicine used to treat schizophrenia and bipolar disorder, helping control hallucinations, delusions, and mood swings.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Lactose Monohydrate
Lactose monohydrate is a sugar substance commonly used as a filler and binder to form tablets and capsules.
Melatonin
Melatonin is a substance that helps regulate the body's sleep-wake cycle and can promote sleep or ease jet lag.
Quetiapine
Quetiapine is a substance that treats schizophrenia and bipolar disorder, helping reduce hallucinations, delusions, and severe mood swings.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adaflex
Alaquet Xl
Anaquetan Xr

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Psykiatrisk Center Kobenhavn
Akutafdelingen, Psykiatrisk Center København
Frederiksberg, Denmark
Sponsor: Region Hovedstadens Psykiatriske
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.