Interstitial Lung Disease: Rituximab and Mycophenolate Combination

We are studying a combination of rituximab and mycophenolate mofetil for patients with interstitial lung disease related to systemic sclerosis. The goal is to see if this treatment improves lung function and overall health compared to a placebo.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Mycophenolate Mofetil
Mycophenolate mofetil is a substance that suppresses the immune system to prevent organ transplant rejection and treat autoimmune conditions.
Mycophenolic Acid
Mycophenolic acid is a substance that suppresses the immune system to help prevent organ transplant rejection and control autoimmune diseases.
Rituximab
Rituximab is a substance that targets and reduces B cells, a type of white blood cell, to treat some blood cancers and autoimmune conditions.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris
Internal Medicine
Angers, France
Centre Hospitalier Universitaire D'Angers
Pneumology
Angers, France
Assistance Publique Hopitaux De Paris
Pneumology
Bagnolet, France

Sponsor: Centre Hospitalier Regional Universitaire De Tours
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.