Pseudoxanthoma Elasticum
Pseudoxanthoma Elasticum (PXE) is a rare genetic disorder that affects the skin, eyes, and cardiovascular system, leading to symptoms like yellowish bumps on the skin, vision problems, and arterial calcification.
INZ-701 for ENPP1 and ABCC6 Deficiency
We are studying the long-term safety of INZ-701 in patients with ENPP1 and ABCC6 deficiencies. This trial will help us understand how the drug works over time and its effects on certain blood markers.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency
Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Deficiency is a rare genetic condition that can lead to generalized arterial calcification and other complications, often presenting in infancy.
Generalized Arterial Calcification of Infancy
Generalized Arterial Calcification of Infancy (GACI) is a rare genetic disorder characterized by the abnormal buildup of calcium in the arteries, which can lead to serious cardiovascular issues in infants.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 1 and 75 years old?
- Are you pregnant or breastfeeding?
- Do you have any major health problems that your doctor has told you about?
- Are you currently taking any investigational drugs or participating in another clinical study?
- Are you a male trying to father a child?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Inz-701
Recombinant Human Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Fused to the Fc Fragment of IgG1
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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CEREDIH Groupe Hospitalier Necker-Enfants Malades
Department of Pediatric Endocrinology, Gynaecology and Diabetology
Montrouge, France
PAREXEL International GmbH
Early Phase Clinical Unit (EPCU) Berlin
Berlin, Germany
University Medical Center Hamburg-Eppendorf
Department of Osteology and Biomechanics
Hamburg, Germany
Sponsor: Inozyme Pharma Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.